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Kinvara Private Hospital

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Patient living free of knee pain after Arthrosamid treatment

Arthrosamid®

Move freely. Live fully.

Long-lasting, proven pain relief for knee osteoarthritis, without surgery. Arthrosamid® is a one-time hydrogel injection that eases pain and restores movement, with results sustained up to 5 years.

Clinically provenLong-lastingNo surgerySame-day procedure
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73%
patients improved
5yr+
sustained relief
30min
in clinic
One
injection
Single hydrogel injection
Arthrosamid®
WOMAC pain reduction
~73%
Maintained for up to
5 yrs
Hospital stay
0 nights
Procedure time
~30 min

Data from prospective clinical studies of intra-articular polyacrylamide hydrogel for knee osteoarthritis. Bliddal H, et al. A Prospective Study of Polyacrylamide Hydrogel Injection for Knee Osteoarthritis: Results from 5 Years After Treatment. Presented at WCO-IOF-ESCEO 2025. See also: Bliddal H, et al. Osteoarthritis and Cartilage. 2024;32(6):770-771.

A new generation of knee injection.

Arthrosamid is a 2.5% polyacrylamide hydrogel. Once injected it doesn't simply float in the joint fluid like older treatments. It meshes with the synovial tissue lining the knee, softening it, restoring elasticity, and easing the inflammation that drives osteoarthritis pain.

The result is a one time, surgery free treatment with pain relief shown to be sustained 5 years after a single injection.

Clinically proven

20+ years of research.

Backed by prospective studies showing significant pain reduction maintained at 5 years.

Long lasting

One injection, years of relief.

A single dose integrates with the synovial lining. No repeat courses. No top up appointments.

No surgery

Out patient. Local anaesthetic.

No general anaesthesia, no overnight stay, no surgical recovery period.

Same day

In and out the same day.

Most patients return to gentle daily activities within 24 to 48 hours.

How it works

From first consultation to lasting relief , in four simple steps.

  1. 1

    Consultation & assessment

    A consultant orthopaedic surgeon confirms knee osteoarthritis with examination and imaging, and discusses whether Arthrosamid® is right for you.

  2. 2

    Preparation

    Antibiotics are given ahead of the procedure. The knee is cleaned and a local anaesthetic numbs the injection site.

  3. 3

    A single injection

    Arthrosamid® is injected once into the knee joint, often with ultrasound guidance for precision. A small plaster covers the site.

  4. 4

    Integration & relief

    Over 6 to 12 weeks the hydrogel meshes with the synovial tissue lining the joint, softening it, restoring elasticity and easing pain.

How it compares

Arthrosamid® vs. the alternatives.

Most knee injections wear off within months. Knee replacement means major surgery. Here's how Arthrosamid® sits between them.

Compared onArthrosamid®Hyaluronic acid (HA)Steroid injectionKnee replacement
Number of treatmentsOne injection3 to 5 injections per courseRepeat every 3 to 6 monthsOne major operation
Duration of reliefUp to 5+ yearsLittle evidence beyond 6 monthsWeeks to a few months15 to 20+ years
Recovery time24 to 48 hours24 to 48 hours24 to 48 hours3 to 6 months
AnaestheticLocalLocalLocalGeneral + nerve block
Hospital stayDay caseDay caseDay case1 to 3 nights

Comparison values reflect general clinical experience and published evidence. Your individual treatment plan will be decided with your consultant.

Patient stories

Real people. Real movement. Back.

I was unable to ski without a brace using hydraulic supports and yet, just two months after Arthrosamid® in both knees, I was on black runs again without any support, it is literally life changing.
Ian, 52
Returned to skiing
My knees were in constant pain and nothing worked. After Arthrosamid®, within a week I was walking more normally again and pain was reduced by about 90%. I have my life back.
Lorraine, 60
Back to walking pain-free
My basketball career felt over and I was about to give in to a knee replacement. After Arthrosamid®, I am pain free and on my way to the European championships as Captain of the GB Masters team.
Paul, 51
Returned to elite sport

Patient testimonials provided with consent via Arthrosamid® patient brochure. Individual results vary; outcomes are not guaranteed.

Is it right for you?

Who Arthrosamid® is , and isn't , for.

A face-to-face consultation with one of our orthopaedic consultants is the only way to know for sure whether Arthrosamid® is appropriate for your knee. As a guide:

You may be a candidate if

  • Adults with diagnosed knee osteoarthritis
  • Pain not adequately controlled by physiotherapy, weight management or oral analgesia
  • Patients wanting to delay or avoid knee replacement surgery
  • Patients in whom previous HA or steroid injections have stopped working
  • Patients who are not yet eligible for, or want to avoid, joint replacement

Arthrosamid® is not suitable if you

  • Active skin infection at or near the knee
  • Active joint infection or severe inflammation
  • Previous treatment with a different non-absorbable injectable / implant
  • Knee replacement (alloplasty) or foreign material already in the knee
  • Knee arthroscopy within the past 6 months
  • Haemophilia or uncontrolled anti-coagulant therapy

Important: There is no cure for osteoarthritis. Treatment with Arthrosamid® may reduce or relieve knee pain, but the underlying arthritis can still progress. Your consultant will discuss expected outcomes and any risks at consultation.

FAQs

What is Arthrosamid?
A 2.5% polyacrylamide hydrogel injected once into the knee joint. It is the first and only approved injectable that permanently combines with the synovial tissue lining the knee, softening it and increasing elasticity to reduce pain and stiffness.
Is it permanent?
Yes. Once injected, Arthrosamid integrates with the synovial lining over 6 to 12 weeks. Clinical studies show pain-relieving effect maintained at 5 years after a single treatment.
How quickly will I feel the benefit?
Many patients notice improvement within the first 1 to 2 weeks, with continued improvement over the following weeks. Full integration takes about 6 to 12 weeks.
How is it different from hyaluronic acid?
HA injections have limited evidence of effect beyond six months and often need to be repeated. Arthrosamid is a single injection with significant pain relief shown to be maintained at five years.
How is it different from a steroid injection?
Steroid injections typically provide short-term relief lasting weeks to a few months and may need to be repeated. Arthrosamid is designed for long-lasting relief from a single treatment.
What are the side effects?
No serious side effects reported in clinical trials. The most commonly reported effects were mild joint pain and a sensation of joint swelling, lasting days to weeks.
Will it cure my arthritis?
No. There is no cure for osteoarthritis. Arthrosamid reduces or relieves the pain of knee OA in most suitable patients. Your underlying arthritis may still progress.
Who is not suitable?
Patients with active skin or joint infection, severe inflammation, prior knee replacement or foreign material in the knee, knee arthroscopy within the last six months, haemophilia, or uncontrolled anti-coagulant therapy.

Message us about Arthrosamid®

Find out whether Arthrosamid® is right for your knee. Fill out the form and a member of our orthopaedic team at Kinvara Private Hospital, Rotherham, will get back to you to discuss your suitability and book a consultation.

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